| Week 8 | |||
| SUN, NOV 1 | TIME (ET) | TV | LOCATION |
| Houston at Buffalo | 1:00 PM | CBS | Ralph Wilson Stadium |
| Cleveland at Chicago | 1:00 PM | CBS | Soldier Field |
| Seattle at Dallas | 1:00 PM | FOX | Dallas Cowboys New Stadium |
| St. Louis at Detroit | 1:00 PM | FOX | Ford Field |
| Minnesota at Green Bay | 1:00 PM | FOX | Lambeau Field |
| San Francisco at Indianapolis | 1:00 PM | FOX | Lucas Oil Stadium |
| Miami at NY Jets | 1:00 PM | CBS | Giants Stadium |
| Denver at Baltimore | 1:00 PM | CBS | M&T Bank Stadium |
| Oakland at San Diego | 4:05 PM | CBS | Qualcomm Stadium |
| Jacksonville at Tennessee | 4:05 PM | CBS | LP Field |
| NY Giants at Philadelphia | 4:15 PM | FOX | Lincoln Financial Field |
| Carolina at Arizona | 4:15 PM | FOX | U of Phoenix Stadium |
| MON, NOV 2 | TIME (ET) | TV | LOCATION |
| Atlanta at New Orleans | 8:30 PM | ESPN | Superdome |
| ·Bye: Cincinnati, Kansas City, New England, Pittsburgh, Tampa Bay, Washington | |||
| Week 9 | |||
| SUN, NOV 8 | TIME (ET) | TV | LOCATION |
| Washington at Atlanta | 1:00 PM | FOX | Georgia Dome |
| Arizona at Chicago | 1:00 PM | FOX | Soldier Field |
| Baltimore at Cincinnati | 1:00 PM | CBS | Paul Brown Stadium |
| Houston at Indianapolis | 1:00 PM | CBS | Lucas Oil Stadium |
| Miami at New England | 1:00 PM | CBS | Gillette Stadium |
| Green Bay at Tampa Bay | 1:00 PM | FOX | Raymond James Stadium |
| Kansas City at Jacksonville | 1:00 PM | CBS | Jacksonville Stadium |
| Detroit at Seattle | 4:05 PM | FOX | Qwest Field |
| Carolina at New Orleans | 4:05 PM | FOX | Superdome |
| San Diego at NY Giants | 4:15 PM | CBS | Giants Stadium |
| Tennessee at San Francisco | 4:15 PM | CBS | Candlestick Park |
| Dallas at Philadelphia | 8:20 PM | NBC | Lincoln Financial Field |
| MON, NOV 9 | TIME (ET) | TV | LOCATION |
| Pittsburgh at Denver | 8:30 PM | ESPN | Invesco Field at Mile High |
| ·Bye: Buffalo, Cleveland, Oakland, St. Louis, Minnesota, NY Jets | |||
| Week 10 | |||
| THU, NOV 12 | TIME (ET) | TV | LOCATION |
| Chicago at San Francisco | 8:20 PM | NFL | Candlestick Park |
| SUN, NOV 15 | TIME (ET) | TV | LOCATION |
| Buffalo at Tennessee | 1:00 PM | CBS | LP Field |
| New Orleans at St. Louis | 1:00 PM | FOX | Edward Jones Dome |
| Tampa Bay at Miami | 1:00 PM | FOX | Dolphin Stadium |
| Detroit at Minnesota | 1:00 PM | FOX | Metrodome |
| Jacksonville at NY Jets | 1:00 PM | CBS | Giants Stadium |
| Cincinnati at Pittsburgh | 1:00 PM | CBS | Heinz Field |
| Denver at Washington | 1:00 PM | CBS | FedEx Field |
| Atlanta at Carolina | 1:00 PM | FOX | Bank of America Stadium |
| Kansas City at Oakland | 4:05 PM | CBS | Oakland-Alameda County Coliseum |
| Dallas at Green Bay | 4:15 PM | FOX | Lambeau Field |
| Seattle at Arizona | 4:15 PM | FOX | U of Phoenix Stadium |
| Philadelphia at San Diego | 4:15 PM | FOX | Qualcomm Stadium |
| New England at Indianapolis | 8:20 PM | NBC | Lucas Oil Stadium |
| MON, NOV 16 | TIME (ET) | TV | LOCATION |
| Baltimore at Cleveland | 8:30 PM | ESPN | Cleveland Browns Stadium |
| ·Bye: NY Giants, Houston | |||
| Week 11 | |||
| THU, NOV 19 | TIME (ET) | TV | LOCATION |
| Miami at Carolina | 8:20 PM | NFL | Bank of America Stadium |
| SUN, NOV 22 | TIME (ET) | TV | LOCATION |
| Washington at Dallas | 1:00 PM | FOX | Dallas Cowboys New Stadium |
| Cleveland at Detroit | 1:00 PM | CBS | Ford Field |
| San Francisco at Green Bay | 1:00 PM | FOX | Lambeau Field |
| Pittsburgh at Kansas City | 1:00 PM | CBS | Arrowhead Stadium |
| Atlanta at NY Giants | 1:00 PM | FOX | Giants Stadium |
| New Orleans at Tampa Bay | 1:00 PM | FOX | Raymond James Stadium |
| Buffalo at Jacksonville | 1:00 PM | CBS | Jacksonville Stadium |
| Indianapolis at Baltimore | 1:00 PM | CBS | M&T Bank Stadium |
| Seattle at Minnesota | 1:00 PM | FOX | Metrodome |
| Arizona at St. Louis | 4:05 PM | FOX | Edward Jones Dome |
| NY Jets at New England | 4:15 PM | CBS | Gillette Stadium |
| Cincinnati at Oakland | 4:15 PM | CBS | Oakland-Alameda County Coliseum |
| San Diego at Denver | 4:15 PM | CBS | Invesco Field at Mile High |
| Philadelphia at Chicago | 8:20 PM | NBC | Soldier Field |
| MON, NOV 23 | TIME (ET) | TV | LOCATION |
| Tennessee at Houston | 8:30 PM | ESPN | Reliant Stadium |
| Week 12 | |||
| THU, NOV 26 | TIME (ET) | TV | LOCATION |
| Green Bay at Detroit | 12:30 PM | FOX | Ford Field |
| Oakland at Dallas | 4:15 PM | CBS | Dallas Cowboys New Stadium |
| NY Giants at Denver | 8:20 PM | NFL | Invesco Field at Mile High |
| SUN, NOV 29 | TIME (ET) | TV | LOCATION |
| Tampa Bay at Atlanta | 1:00 PM | FOX | Georgia Dome |
| Miami at Buffalo | 1:00 PM | CBS | Ralph Wilson Stadium |
| Cleveland at Cincinnati | 1:00 PM | CBS | Paul Brown Stadium |
| Arizona at Tennessee | 1:00 PM | FOX | LP Field |
| Seattle at St. Louis | 1:00 PM | FOX | Edward Jones Dome |
| Chicago at Minnesota | 1:00 PM | FOX | Metrodome |
| Carolina at NY Jets | 1:00 PM | FOX | Giants Stadium |
| Washington at Philadelphia | 1:00 PM | FOX | Lincoln Financial Field |
| Indianapolis at Houston | 1:00 PM | CBS | Reliant Stadium |
| Kansas City at San Diego | 4:05 PM | CBS | Qualcomm Stadium |
| Jacksonville at San Francisco | 4:05 PM | CBS | Candlestick Park |
| Pittsburgh at Baltimore | 8:20 PM | NBC | M&T Bank Stadium |
| MON, NOV 30 | TIME (ET) | TV | LOCATION |
| New England at New Orleans | 8:30 PM | ESPN | Superdome |
| Week 13 | |||
| THU, DEC 3 | TIME (ET) | TV | LOCATION |
| NY Jets at Buffalo | 8:20 PM | NFL | Rogers Centre |
| SUN, DEC 6 | TIME (ET) | TV | LOCATION |
| Philadelphia at Atlanta | 1:00 PM | FOX | Georgia Dome |
| St. Louis at Chicago | 1:00 PM | FOX | Soldier Field |
| Detroit at Cincinnati | 1:00 PM | FOX | Paul Brown Stadium |
| Tennessee at Indianapolis | 1:00 PM | CBS | Lucas Oil Stadium |
| Denver at Kansas City | 1:00 PM | CBS | Arrowhead Stadium |
| New Orleans at Washington | 1:00 PM | FOX | FedEx Field |
| Tampa Bay at Carolina | 1:00 PM | FOX | Bank of America Stadium |
| Houston at Jacksonville | 1:00 PM | CBS | Jacksonville Stadium |
| Oakland at Pittsburgh | 1:00 PM | CBS | Heinz Field |
| San Diego at Cleveland | 4:05 PM | CBS | Cleveland Browns Stadium |
| San Francisco at Seattle | 4:15 PM | FOX | Qwest Field |
| Dallas at NY Giants | 4:15 PM | FOX | Giants Stadium |
| Minnesota at Arizona | 4:15 PM | FOX | U of Phoenix Stadium |
| New England at Miami | 8:20 PM | NBC | Dolphin Stadium |
| MON, DEC 7 | TIME (ET) | TV | LOCATION |
| Baltimore at Green Bay | 8:30 PM | ESPN | Lambeau Field |
| Week 14 | |||
| THU, DEC 10 | TIME (ET) | TV | LOCATION |
| Pittsburgh at Cleveland | 8:20 PM | NFL | Cleveland Browns Stadium |
| SUN, DEC 13 | TIME (ET) | TV | LOCATION |
| New Orleans at Atlanta | 1:00 PM | FOX | Georgia Dome |
| Green Bay at Chicago | 1:00 PM | FOX | Soldier Field |
| St. Louis at Tennessee | 1:00 PM | FOX | LP Field |
| Denver at Indianapolis | 1:00 PM | CBS | Lucas Oil Stadium |
| Buffalo at Kansas City | 1:00 PM | CBS | Arrowhead Stadium |
| NY Jets at Tampa Bay | 1:00 PM | CBS | Raymond James Stadium |
| Miami at Jacksonville | 1:00 PM | CBS | Jacksonville Stadium |
| Detroit at Baltimore | 1:00 PM | FOX | M&T Bank Stadium |
| Seattle at Houston | 1:00 PM | FOX | Reliant Stadium |
| Cincinnati at Minnesota | 1:00 PM | CBS | Metrodome |
| Carolina at New England | 1:00 PM | FOX | Gillette Stadium |
| Washington at Oakland | 4:05 PM | FOX | Oakland-Alameda County Coliseum |
| San Diego at Dallas | 4:15 PM | CBS | Dallas Cowboys New Stadium |
| Philadelphia at NY Giants | 8:20 PM | NBC | Giants Stadium |
| MON, DEC 14 | TIME (ET) | TV | LOCATION |
| Arizona at San Francisco | 8:30 PM | ESPN | Candlestick Park |
| Week 15 | |||
| THU, DEC 17 | TIME (ET) | TV | LOCATION |
| Indianapolis at Jacksonville | 8:20 PM | NFL | Jacksonville Stadium |
| SAT, DEC 19 | TIME (ET) | TV | LOCATION |
| Dallas at New Orleans | 8:20 PM | NFL | Superdome |
| SUN, DEC 20 | TIME (ET) | TV | LOCATION |
| New England at Buffalo | 1:00 PM | CBS | Ralph Wilson Stadium |
| Arizona at Detroit | 1:00 PM | FOX | Ford Field |
| Miami at Tennessee | 1:00 PM | CBS | LP Field |
| Cleveland at Kansas City | 1:00 PM | CBS | Arrowhead Stadium |
| Houston at St. Louis | 1:00 PM | CBS | Edward Jones Dome |
| Atlanta at NY Jets | 1:00 PM | FOX | Giants Stadium |
| San Francisco at Philadelphia | 1:00 PM | FOX | Lincoln Financial Field |
| Green Bay at Pittsburgh | 1:00 PM | FOX | Heinz Field |
| Chicago at Baltimore | 1:00 PM | FOX | M&T Bank Stadium |
| Cincinnati at San Diego | 4:05 PM | CBS | Qualcomm Stadium |
| Oakland at Denver | 4:05 PM | CBS | Invesco Field at Mile High |
| Tampa Bay at Seattle | 4:15 PM | FOX | Qwest Field |
| Minnesota at Carolina | 8:20 PM | NBC | Bank of America Stadium |
| MON, DEC 21 | TIME (ET) | TV | LOCATION |
| NY Giants at Washington | 8:30 PM | ESPN | FedEx Field |
| Week 16 | |||
| FRI, DEC 25 | TIME (ET) | TV | LOCATION |
| San Diego at Tennessee | 7:30 PM | NFL | LP Field |
| SUN, DEC 27 | TIME (ET) | TV | LOCATION |
| Buffalo at Atlanta | 1:00 PM | CBS | Georgia Dome |
| Kansas City at Cincinnati | 1:00 PM | CBS | Paul Brown Stadium |
| Oakland at Cleveland | 1:00 PM | CBS | Cleveland Browns Stadium |
| Seattle at Green Bay | 1:00 PM | FOX | Lambeau Field |
| Baltimore at Pittsburgh | 1:00 PM | CBS | Heinz Field |
| Houston at Miami | 1:00 PM | CBS | Dolphin Stadium |
| Jacksonville at New England | 1:00 PM | CBS | Gillette Stadium |
| Tampa Bay at New Orleans | 1:00 PM | FOX | Superdome |
| Carolina at NY Giants | 1:00 PM | FOX | Giants Stadium |
| Denver at Philadelphia | 1:00 PM | CBS | Lincoln Financial Field |
| St. Louis at Arizona | 4:05 PM | FOX | U of Phoenix Stadium |
| Detroit at San Francisco | 4:05 PM | FOX | Candlestick Park |
| NY Jets at Indianapolis | 4:15 PM | CBS | Lucas Oil Stadium |
| Dallas at Washington | 8:20 PM | NBC | FedEx Field |
| MON, DEC 28 | TIME (ET) | TV | LOCATION |
| Minnesota at Chicago | 8:30 PM | ESPN | Soldier Field |
| Week 17 | |||
| SUN, JAN 3 | TIME (ET) | TV | LOCATION |
| Indianapolis at Buffalo | 1:00 PM | CBS | Ralph Wilson Stadium |
| Jacksonville at Cleveland | 1:00 PM | CBS | Cleveland Browns Stadium |
| Philadelphia at Dallas | 1:00 PM | FOX | Dallas Cowboys New Stadium |
| Chicago at Detroit | 1:00 PM | FOX | Ford Field |
| Atlanta at Tampa Bay | 1:00 PM | FOX | Raymond James Stadium |
| New Orleans at Carolina | 1:00 PM | FOX | Bank of America Stadium |
| New England at Houston | 1:00 PM | CBS | Reliant Stadium |
| San Francisco at St. Louis | 1:00 PM | FOX | Edward Jones Dome |
| Pittsburgh at Miami | 1:00 PM | CBS | Dolphin Stadium |
| NY Giants at Minnesota | 1:00 PM | FOX | Metrodome |
| Cincinnati at NY Jets | 1:00 PM | CBS | Giants Stadium |
| Green Bay at Arizona | 4:15 PM | FOX | U of Phoenix Stadium |
| Washington at San Diego | 4:15 PM | FOX | Qualcomm Stadium |
| Tennessee at Seattle | 4:15 PM | CBS | Qwest Field |
| Baltimore at Oakland | 4:15 PM | CBS | Oakland-Alameda County Coliseum |
| Kansas City at Denver | 4:15 PM | CBS | Invesco Field at Mile High |